Publications

Years 2020-2025

1. Zattarin E, Marra A, Palazzo A, Griguolo G, Vernieri C, Etessami J, Pontolillo L, Landa G, Daneri A, De Monte M, Cuoghi Costantini R, Tenedini E, Ponzoni O, Razeti MG, Sposetti C, Barbieri E, Manni M, Caggia F, Cortesi L, Curigliano G, Bria E, Dominici M, Guarneri V, Lambertini M, Toss A. Real-world effectiveness of PARP inhibitors after CDK4/6 inhibitor therapy in BRCA-mutated HR-positive/HER2-negative advanced breast cancer. NPJ Breast Cancer. 2025 Dec 13;11(1):145. doi: 10.1038/s41523-025-00859-z. PMID: 41390667; PMCID: PMC12717040.
2. Toss A, Blondeaux E, Tenedini E, Bonamici L, Graffeo R, Livraghi L, Villarreal-Garza C, Bernstein Molho R, Kwong A, Balmana J, Wildiers H, Agostinetto E, Phillips KA, Pogoda K, Renaud T, Rousset-Jablonski C, Ferrari A, Moore HCF, Peccatori FA, Paluch-Shimon S, Fruscio R, Micheri C, Wong SM, Cui W, Vernieri C, Lee MK, De Marchis L, Couch FJ, Del Mastro L, Puglisi F, Meireles PA, Kemp Z, Matikas A, Plichta J, Del Pilar Estevez-Diz M, Di Meglio A, Cichowska-Cwalinska N, Gianni C, Yerushalmi R, Sanchez-Bayona R, Mrinakova B, Matos L, Bianchini G, Caleffi M, Krivokuca A, Abdou Y, Mariño-Mariño M, Parokonnaya A, Okano M, Antone N, Saavedra C, Sonnenblick A, Duchnowska R, Pais HL, Harbeck N, Cortesi L, Delucchi V, De Angelis C, Lambertini M. Association between type and location of germline BRCA1/2 pathogenic or likely pathogenic variants with phenotype and prognosis in young patients with breast cancer: results from an international cohort study. Ann Oncol. 2025 Nov 17:S0923-7534(25)06262-3. doi: 10.1016/j.annonc.2025.11.004. Epub ahead of print. PMID: 41260260.
3. Cabrera-Serrano AJ, Sánchez-Maldonado JM, Rodríguez-Sevilla JJ, Reyes-Zurita FJ, Collado R, Puiggros A, Cornejo-Calvo E, García-Martín P, Ter Horst R, Benavente Y, Jerez A, Landi S, Espinet B, Maffei R, López-Nevot MÁ, Ramos-Campoy S, González-Olmedo C, Chen-Liang TH, Moreno V, Jannus F, Marcos-Gragera R, Carretero-Fernández M, Sampaio-Marques B, Gámez I, García-Álvarez M, Camp NJ, Dierssen-Sotos T, Kamaso J, Pérez EM, Norman AD, Luppi M, Li Y, Alcoceba M, Campa D, de San José S, Marasca R, Ludovico P, Clay-Gilmour A, Canzian F, Ibañez M, Netea MG, McKay J, Casabonne D, Berndt SI, Slager SL, Sainz J. Identification of 4 autophagy-related genetic variants as risk factors for chronic lymphocytic leukemia. Blood Adv. 2025 Dec 9;9(23):6076-6089. doi: 10.1182/bloodadvances.2025017345. PMID: 40902075; PMCID: PMC12686701.
4. Mirabile M, Tombari C, Neroni A, Tavernari L, Norfo R, Bianchi E, Maccaferri M, Mora B, Parenti S, Carretta C, Bertesi M, Malerba M, Papa E, Fabbiani L, Bartalucci N, Guglielmelli P, Potenza L, Losi L, Passamonti F, Tagliafico E, Luppi M, Rontauroli S, Vannucchi AM, Manfredini R; MYNERVA (Myeloid NEoplasms Research Venture AIRC) investigators. CD44 Participates to Extramedullary Haematopoiesis Onset by Mediating the Interplay Between Monocytes and Haematopoietic Stem Cells in Myelofibrosis. J Cell Mol Med. 2025 Jul;29(14):e70720. doi: 10.1111/jcmm.70720. PMID: 40690545; PMCID: PMC12279041.
5. Giovanella S, Poyatos-Andújar AM, Garcia MMA, Avila-Fernandez A, Bustamante-Aragonés A, Ayuso C, Percesepe A, Martorana D, Ferri M, Terracciano A, Massella L, Chester J, Testa F, Ligabue G, Ferrarini M, Gibertoni D, Alfano G, Tenedini E, Artuso L, Marino M, Calabrese O, Tagliafico E, Magistroni R. Diagnostic Yield and Clinical Impact of a Small Genetic Panel for Kidney Disease: A Multicenter, Retrospective European Study. Clin Genet. 2025 Jun 18. doi: 10.1111/cge.70002. Epub ahead of print. PMID: 40533884.
6. Sighinolfi G, Grandi G, Barbieri E, Venturelli M, Piombino C, Melotti C, Lippi Bruni R, Costantini Cuoghi R, D’Amico R, Lambertini M, Peccatori FA, Tenedini E, Dominici M, Cortesi L, La Marca A, Toss A. Reduced reproductive potential in young healthy women with hereditary breast and/or ovarian cancer syndrome. Commun Med (Lond). 2025 Mar 8;5(1):70. doi: 10.1038/s43856-025-00788-9. PMID: 40057639; PMCID: PMC11890596.
7. Maffei R, Paolini A, Conte B, Riva G, Nasillo V, Cretì F, Martinelli S, Giacobbi F, Corradini G, Pilato F, Bernabei D, Lancellotti C, Debbia G, Morselli M, Potenza L, Giusti D, Colaci E, Bettelli F, Bresciani P, Cuoghi A, Gilioli A, Messerotti A, Pioli V, Maccaferri M, Leonardi G, Manfredini R, Marasca R, Eccher A, Luppi M, Forghieri F, Candoni A, Tagliafico E. Distribution of different classes of CSF3R mutations and co-mutational pattern in 360 myeloid neoplasia. Ann Hematol. 2025 Jan;104(1):263-274. doi: 10.1007/s00277-025-06232-1. Epub 2025 Feb 5. PMID: 39907800; PMCID: PMC11868254.
8. Bardasi C, Tenedini E, Bonamici L, Benatti S, Bonetti LR, Luppi G, Cortesi L, Tagliafico E, Dominici M, Gelsomino F. Homologous recombination deficiency in pancreatic neuroendocrine tumors. Future Oncol. 2024 Dec;20(39):3257-3266. doi: 10.1080/14796694.2024.2421160. Epub 2024 Nov 25. PMID: 39582314; PMCID: PMC11633435.
9. Trevisani V, Palandri L, Righi B, Maione D, De Pasquale L, Tagliafico E, Grisolia C, Tagliazucchi M, Predieri B, Iughetti L, Righi E, Lucaccioni L. The assessment of urinary sexual hormones within minipuberty and correlations with anthropometrics in a cohort of healthy term children. J Endocrinol Invest. 2024 Nov 4. doi: 10.1007/s40618-024-02493-1. Epub ahead of print. PMID: 39489862.
10. Carretta C, Parenti S, Bertesi M, Rontauroli S, Badii F, Tavernari L, Genovese E, Malerba M, Papa E, Sperduti S, Enzo E, Mirabile M, Pedrazzi F, Neroni A, Tombari C, Mora B, Maffioli M, Mondini M, Brociner M, Maccaferri M, Tenedini E, Martinelli S, Bartalucci N, Bianchi E, Casarini L, Potenza L, Luppi M, Tagliafico E, Guglielmelli P, Simoni M, Passamonti F, Norfo R, Vannucchi AM, Manfredini R; MYNERVA (Myeloid NEoplasms Research Venture AIRC). Chromosome 9p trisomy increases stem cells clonogenic potential and fosters T-cell exhaustion in JAK2-mutant myeloproliferative neoplasms. Leukemia. 2024 Oct;38(10):2171-2182. doi: 10.1038/s41375-024-02373-w. Epub 2024 Aug 23. PMID: 39179669; PMCID: PMC11436358.
11. Bettelli F, Vallerini D, Lagreca I, Barozzi P, Riva G, Nasillo V, Paolini A, D’Amico R, Forghieri F, Morselli M, Pioli V, Gilioli A, Giusti D, Messerotti A, Bresciani P, Cuoghi A, Colaci E, Marasca R, Pagano L, Candoni A, Maertens J, Viale P, Mussini C, Manfredini R, Tagliafico E, Sarti M, Trenti T, Lewis R, Comoli P, Eccher A, Luppi M, Potenza L. Identification and validation of diagnostic cut-offs of the ELISpot assay for the diagnosis of invasive aspergillosis in high-risk patients. PLoS One. 2024 Jul 9;19(7):e0306728. doi: 10.1371/journal.pone.0306728. PMID: 38980880; PMCID: PMC11233002.
12. Tavernari L, Rontauroli S, Norfo R, Mirabile M, Maccaferri M, Mora B, Genovese E, Parenti S, Carretta C, Bianchi E, Bertesi M, Pedrazzi F, Tenedini E, Martinelli S, Bochicchio MT, Guglielmelli P, Potenza L, Lucchesi A, Passamonti F, Tagliafico E, Luppi M, Vannucchi AM, Manfredini R; MYNERVA (Myeloid NEoplasms Research Venture AIRC) investigators. Targeting exhausted cytotoxic T cells through CTLA-4 inhibition promotes elimination of neoplastic cells in human myelofibrosis xenografts. Am J Hematol. 2024 Jul 2. doi: 10.1002/ajh.27428. Epub ahead of print. PMID: 38953347.
13. Mutti M, Cordella S, Parisotto A, Bettelli F, Morselli M, Cuoghi A, Bresciani P, Messerotti A, Gilioli A, Pioli V, Giusti D, Colaci E, Cassanelli L, Paolini A, Martinelli S, Maffei R, Riva G, Nasillo V, Sarti M, Trenti T, Comoli P, Tagliafico E, Manfredini R, Eccher A, Lagreca I, Barozzi P, Potenza L, Marasca R, Candoni A, Luppi M, Forghieri F. Characteristics and clinical behavior of acute myeloid leukemia harboring rare non-A/B/D nucleophosmin (NPM1) gene mutation subtypes: a single-center experience and review of the literature. Leuk Lymphoma. 2023 Dec 19:1-5. doi: 10.1080/10428194.2023.2294695. Epub ahead of print. PMID: 38112426.
14. Toss A, Ponzoni O, Riccò B, Piombino C, Moscetti L, Combi F, Palma E, Papi S, Tenedini E, Tazzioli G, Dominici M, Cortesi L. Management of PALB2-associated breast cancer: A literature review and case report. Clin Case Rep. 2023 Aug 22;11(8):e7747. doi: 10.1002/ccr3.7747. PMID: 37621724; PMCID: PMC10444947.
15. Cattaneo C, Enzo E, De Rosa L, Sercia L, Consiglio F, Forcato M, Bicciato S, Paiardini A, Basso G, Tagliafico E, Paganelli A, Fiorentini C, Magnoni C, Latella MC, De Luca M. Allele-specific CRISPR-Cas9 editing of dominant epidermolysis bullosa simplex in human epidermal stem cells. Mol Ther. 2024 Feb 7;32(2):372-383. doi: 10.1016/j.ymthe.2023.11.027. Epub 2023 Dec 5. PMID: 38053334.
16. Dieci MV, Conte PP, Bisagni PG, Bartolini S, Frassoldati A, Generali D, Piacentini F, Griguolo G, Tagliafico E, Brasó Maristany F, Chic N, Paré L, Miglietta F, Vicini R, D’Amico R, Balduzzi S, Prat A, Guarneri V. Metastatic site patterns by intrinsic subtype and HER2DX in early HER2-positive breast cancer. J Natl Cancer Inst. 2023 Sep 7:djad179. doi: 10.1093/jnci/djad179. Epub ahead of print. PMID: 37676829.
17. Cabrera-Serrano AJ, Sánchez-Maldonado JM, Ter Horst R, Macauda A, García-Martín P, Benavente Y, Landi S, Clay-Gilmour A, Niazi Y, Espinet B, Rodríguez-Sevilla JJ, Pérez EM, Maffei R, Blanco G, Giaccherini M, Cerhan JR, Marasca R, López-Nevot MÁ, Chen-Liang T, Thomsen H, Gámez I, Campa D, Moreno V, de Sanjosé S, Marcos-Gragera R, García-Álvarez M, Dierssen-Sotos T, Jerez A, Butrym A, Norman AD, Luppi M, Slager SL, Hemminki K, Li Y, Berndt SI, Casabonne D, Alcoceba M, Puiggros A, Netea MG, Försti A, Canzian F, Sainz J. Do GWAS-Identified Risk Variants for Chronic Lymphocytic Leukemia Influence Overall Patient Survival and Disease Progression? Int J Mol Sci. 2023 Apr 28;24(9):8005. doi: 10.3390/ijms24098005. PMID: 37175717; PMCID: PMC10178669.
18. Mesini N, Fiorcari S, Atene CG, Maffei R, Potenza L, Luppi M, Marasca R. Role of Notch2 pathway in mature B cell malignancies. Front Oncol. 2023 Jan 4;12:1073672. doi: 10.3389/fonc.2022.1073672. PMID: 36686759; PMCID: PMC9846264.
19. Moia R, Terzi di Bergamo L, Talotta D, Bomben R, Forestieri G, Spina V, Bruscaggin A, Cosentino C, Almasri M, Dondolin R, Bittolo T, Zucchetto A, Baldoni S, Del Giudice I, Mauro FR, Maffei R, Chiarenza A, Tafuri A, Laureana R, Del Principe MI, Zaja F, D’Arena G, Olivieri J, Rasi S, Mahmoud A, Al Essa W, Awikeh B, Kogila S, Bellia M, Mouhssine S, Sportoletti P, Marasca R, Scarfò L, Ghia P, Gattei V, Foà R, Rossi D, Gaidano G. XPO1 mutations identify early-stage CLL characterized by shorter time to first treatment and enhanced BCR signalling. Br J Haematol. 2023 Nov;203(3):416-425. doi: 10.1111/bjh.19052. Epub 2023 Aug 14. PMID: 37580908.
20. Boncompagni A, Pietrella E, Passini E, Grisolia C, Tagliazucchi M, Tagliafico E, Lugli L, Berardi A, Iughetti L, Lucaccioni L. Minipuberty in Male Full-term Neonates Appropriate and Small for Gestational Age and in Preterm Babies: Data From a Single Centre. J Clin Res Pediatr Endocrinol. 2023 Sep 26. doi: 10.4274/jcrpe.galenos.2023.2023-4-9. Epub ahead of print. PMID: 37750394.
21. Riva G, Luppi M, Tagliafico E. From gating to computational flow cytometry: Exploiting artificial intelligence for MRD diagnostics. Br J Haematol. 2023 Aug;202(4):715-717. doi: 10.1111/bjh.18833. Epub 2023 Apr 24. PMID: 37092558.
22. Bianchi E, Rontauroli S, Tavernari L, Mirabile M, Pedrazzi F, Genovese E, Sartini S, Dall’Ora M, Grisendi G, Fabbiani L, Maccaferri M, Carretta C, Parenti S, Fantini S, Bartalucci N, Calabresi L, Balliu M, Guglielmelli P, Potenza L, Tagliafico E, Losi L, Dominici M, Luppi M, Vannucchi AM, Manfredini R. Inhibition of ERK1/2 signaling prevents bone marrow fibrosis by reducing osteopontin plasma levels in a myelofibrosis mouse model. Leukemia. 2023 Mar 16. doi: 10.1038/s41375-023-01867-3. Epub ahead of print. PMID: 36928007.
23. Lagreca I, Nasillo V, Barozzi P, Castelli I, Basso S, Castellano S, Paolini A, Maccaferri M, Colaci E, Vallerini D, Natali P, Debbia D, Pirotti T, Ottomano AM, Maffei R, Bettelli F, Giusti D, Messerotti A, Gilioli A, Pioli V, Leonardi G, Forghieri F, Bresciani P, Cuoghi A, Morselli M, Manfredini R, Longo G, Candoni A, Marasca R, Potenza L, Tagliafico E, Trenti T, Comoli P, Luppi M, Riva G. Prognostic Relevance of Multi-Antigenic Myeloma-Specific T-Cell Assay in Patients with Monoclonal Gammopathies. Cancers (Basel). 2023 Feb 3;15(3):972. doi: 10.3390/cancers15030972. PMID: 36765928; PMCID: PMC9913154.
24. Maffei R, Fiorcari S, Atene CG, Martinelli S, Mesini N, Pilato F, Lagreca I, Barozzi P, Riva G, Nasillo V, Paolini A, Forghieri F, Potenza L, Trenti T, Tagliafico E, Luppi M, Marasca R. The dynamic functions of IRF4 in B cell malignancies. Clin Exp Med. 2022 Dec 10. doi: 10.1007/s10238-022-00968-0. Epub ahead of print. PMID: 36495369.
25. Cordella S, Parisotto A, Bettelli F, Morselli M, Barbieri E, Pozzi S, Aquilino A, Repaci G, Cuoghi A, Bresciani P, Messerotti A, Colasante C, Gilioli A, Pioli V, Giusti D, Colaci E, Cassanelli L, Ceccherelli G, Bevini M, Malavolti R, Venturelli D, Paolini A, Martinelli S, Maffei R, Riva G, Nasillo V, Trenti T, Comoli P, Tagliafico E, Manfredini R, Barozzi P, Potenza L, Marasca R, Luppi M, Forghieri F. Feasibility of autologous peripheral blood stem cell mobilization and harvest in adult patients with FLT3-mutated acute myeloid leukemia receiving chemotherapy combined with midostaurin: a single-center experience. Ann Hematol. 2023 Jan;102(1):213-217. doi: 10.1007/s00277-022-05013-4. Epub 2022 Oct 20. PMID: 36261597.
26. Tenedini E, Piana S, Toss A, Marino M, Barbieri E, Artuso L, Venturelli M, Gasparini E, Mandato VD, Marchi I, Castellano S, Luppi M, Trenti T, Cortesi L, Tagliafico E. Constitutional Mosaicism: A Critical Issue in the Definition of BRCA-Inherited Cancer Risk. JCO Precis Oncol. 2022 Aug;6:e2200138. doi: 10.1200/PO.22.00138. PMID: 36075010; PMCID: PMC9489180.
27. García-Martín P, Díez AM, Maldonado JMS, Serrano AJC, Ter Horst R, Benavente Y, Landi S, Macauda A, Clay-Gilmour A, Hernández-Mohedo F, Niazi Y, González-Sierra P, Espinet B, Rodríguez-Sevilla JJ, Maffei R, Blanco G, Giaccherini M, Puiggros A, Cerhan J, Marasca R, Cañadas-Garre M, López-Nevot MÁ, Chen-Liang T, Thomsen H, Gámez I, Moreno V, Marcos-Gragera R, García-Álvarez M, Llorca J, Jerez A, Berndt S, Butrym A, Norman AD, Casabonne D, Luppi M, Slager SL, Hemminki K, Li Y, Alcoceba M, Campa D, Canzian F, de Sanjosé S, Försti A, Netea MG, Jurado M, Sainz J. Validation and functional characterization of GWAS-identified variants for chronic lymphocytic leukemia: a CRuCIAL study. Blood Cancer J. 2022 May 17;12(5):79. doi: 10.1038/s41408-022-00676-8. PMID: 35581176; PMCID: PMC9114372.
28. Fiorcari S, Maffei R, Atene CG, Mesini N, Maccaferri M, Leonardi G, Martinelli S, Paolini A, Nasillo V, Debbia G, Potenza L, Luppi M, Marasca R. Notch2 Increases the Resistance to Venetoclax-Induced Apoptosis in Chronic Lymphocytic Leukemia B Cells by Inducing Mcl-1. Front Oncol. 2022 Jan 6;11:777587. doi: 10.3389/fonc.2021.777587. PMID: 35070982; PMCID: PMC8770925.
29. Giovanella S, Pasini A, Ligabue G, Testa F, Mori G, Tagliafico E, Magistroni R. PAX2/Renal Coloboma Syndrome Expresses Extreme Intrafamilial Phenotypic Variability. Nephron. 2022 Jul 5:1-7. doi: 10.1159/000525022. Epub ahead of print. PMID: 35790137.
30. Russo A, Incorvaia L, Capoluongo E, Tagliaferri P, Gori S, Cortesi L, Genuardi M, Turchetti D, De Giorgi U, Di Maio M, Barberis M, Dessena M, Del Re M, Lapini A, Luchini C, Jereczek-Fossa BA, Sapino A, Cinieri S; Italian Scientific Societies. Implementation of preventive and predictive BRCA testing in patients with breast, ovarian, pancreatic, and prostate cancer: a position paper of Italian Scientific Societies. ESMO Open. 2022 May 18;7(3):100459. doi: 10.1016/j.esmoop.2022.100459. Epub ahead of print. PMID: 35597177.
31. Lagreca I, Riva G, Nasillo V, Barozzi P, Castelli I, Basso S, Bettelli F, Giusti D, Cuoghi A, Bresciani P, Messerotti A, Gilioli A, Pioli V, Colasante C, Vallerini D, Paolini A, Maccaferri M, Donatelli F, Forghieri F, Morselli M, Colaci E, Leonardi G, Marasca R, Potenza L, Manfredini R, Tagliafico E, Trenti T, Comoli P, Luppi M. The Role of T Cell Immunity in Monoclonal Gammopathy and Multiple Myeloma: From Immunopathogenesis to Novel Therapeutic Approaches. Int J Mol Sci. 2022 May 8;23(9):5242. doi: 10.3390/ijms23095242. PMID: 35563634; PMCID: PMC9104275.
32. Nasillo V, Lagreca I, Vallerini D, Barozzi P, Riva G, Maccaferri M, Paolini A, Forghieri F, Fiorcari S, Maffei R, Martinelli S, Atene CG, Castelli I, Marasca R, Potenza L, Comoli P, Manfredini R, Tagliafico E, Trenti T, Luppi M. BTK Inhibitors Impair Platelet-Mediated Antifungal Activity. Cells. 2022 Mar 16;11(6):1003. doi: 10.3390/cells11061003. PMID: 35326454.
33. Genovese, E.; Mirabile, M.; Rontauroli, S.; Sartini, S.; Fantini, S.; Tavernari, L.; Maccaferri, M.; Guglielmelli, P.; Bianchi, E.; Parenti, S.; Carretta, C.; Mallia, S.; Castellano, S.; Colasante, C.; Balliu, M.; Bartalucci, N.; Palmieri, R.; Ottone, T.; Mora, B.; Potenza, L.; Passamonti, F.; Voso, M.T.; Luppi, M.; Vannucchi, A.M.; Tagliafico, E.; Manfredini, R.; on behalf of the Mynerva. The Response to Oxidative Damage Correlates with Driver Mutations and Clinical Outcome in Patients with Myelofibrosis. Antioxidants 2022, 11, 113. https://doi.org/10.3390/antiox11010113
34. Talami A, Bettelli F, Pioli V, Giusti D, Gilioli A, Colasante C, Galassi L,Giubbolini R, Catellani H, Donatelli F, Maffei R, Martinelli S, Barozzi P,Potenza L, Marasca R, Trenti T, Tagliafico E, Comoli P, Luppi M, Forghieri F.How to Improve Prognostication in Acute Myeloid Leukemia with CBFB-MYH11 Fusion Transcript: Focus on the Role of Molecular Measurable Residual Disease(MRD) Monitoring. Biomedicines. 2021 Aug 3;9(8):953. doi:10.3390/biomedicines9080953. PMID: 34440157
35. Benatti S, Atene CG, Fiorcari S, Mesini N, Martinelli S, Zucchini P, Bacchelli F, Maccaferri M, Debbia G, Potenza L, Rossi D, Vallisa D, Trentin L, Gaidano G, Luppi M, Marasca R, Maffei R. IRF4 L116R mutation promotes proliferation of chronic lymphocytic leukemia B cells inducing MYC. Hematol Oncol. 2021 Dec;39(5):707-711. doi: 10.1002/hon.2915. Epub 2021 Aug 25. PMID: 34431535.
36. Fiorcari S, Maffei R, Atene CG, Potenza L, Luppi M, Marasca R. Nurse-Like Cells and Chronic Lymphocytic Leukemia B Cells: A Mutualistic Crosstalk inside Tissue Microenvironments. Cells. 2021 Jan 22;10(2):217. doi: 10.3390/cells10020217. PMID: 33499012; PMCID: PMC7911538.
37. Fiorcari S, Atene CG, Maffei R, Debbia G, Potenza L, Luppi M, Marasca R. Ibrutinib interferes with innate immunity in chronic lymphocytic leukemia patients during COVID-19 infection. Haematologica. 2021 Aug 1;106(8):2265-2268. doi: 10.3324/haematol.2020.277392. PMID: 33691383; PMCID: PMC8327720.
38. Maffei R, Fiorcari S, Benatti S, Atene CG, Martinelli S, Zucchini P, Potenza L, Luppi M, Marasca R. IRF4 modulates the response to BCR activation in chronic lymphocytic leukemia regulating IKAROS and SYK. Leukemia. 2021 May;35(5):1330-1343. doi: 10.1038/s41375-021-01178-5. Epub 2021 Feb 23. PMID: 33623139.
39. Forghieri F, Riva G, Lagreca I, Barozzi P, Bettelli F, Paolini A, Nasillo V,Lusenti B, Pioli V, Giusti D, Gilioli A, Colasante C, Galassi L, Catellani H,Donatelli F, Talami A, Maffei R, Martinelli S, Potenza L, Marasca R, TagliaficoE, Manfredini R, Trenti T, Comoli P, Luppi M. Neoantigen-Specific T-Cell ImmuneResponses: The Paradigm of NPM1-Mutated Acute Myeloid Leukemia. Int J Mol Sci.2021 Aug 25;22(17):9159. doi: 10.3390/ijms22179159. PMID: 34502069
40. Riva G, Nasillo V, Ottomano AM, Bergonzini G, Paolini A, Forghieri F, LusentiB, Barozzi P, Lagreca I, Fiorcari S, Martinelli S, Maffei R, Marasca R, PotenzaL, Comoli P, Manfredini R, Tagliafico E, Trenti T, Luppi M. Multiparametric FlowCytometry for MRD Monitoring in Hematologic Malignancies: Clinical Applications and New Challenges. Cancers (Basel). 2021 Sep 12;13(18):4582. doi:10.3390/cancers13184582. PMID: 34572809
41. Fantini S, Rontauroli S, Sartini S, Mirabile M, Bianchi E, Badii F,Maccaferri M, Guglielmelli P, Ottone T, Palmieri R, Genovese E, Carretta C, Parenti S, Mallia S, Tavernari L, Salvadori C, Gesullo F, Maccari C, Zizza M,Grande A, Salmoiraghi S, Mora B, Potenza L, Rosti V, Passamonti F, Rambaldi A,Voso MT, Mecucci C, Tagliafico E, Luppi M, Vannucchi AM, Manfredini R. IncreasedPlasma Levels of lncRNAs LINC01268,GAS5 and MALAT1 Correlate with Negative Prognostic Factors in Myelofibrosis. Cancers (Basel).2021 Sep 22;13(19):4744. doi: 10.3390/cancers13194744. PMID: 34638230
42. Galassi L, Colasante C, Bettelli F, Gilioli A, Pioli V, Giusti D, Morselli M,Paolini A, Nasillo V, Lusenti B, Colaci E, Donatelli F, Catellani H, Pozzi S,Barbieri E, Del Rosso MN, Barozzi P, Lagreca I, Martinelli S, Maffei R, Riva G,Tenedini E, Roncati L, Marasca R, Potenza L, Comoli P, Trenti T, Manfredini R,Tagliafico E, Luppi M, Forghieri F. Pre-existing cytopenia heralding de novoacute myeloid leukemia: Uncommon presentation of NPM1-mutated AML in a single-center study. Leuk Res. 2021 Dec;111:106747. doi: 10.1016/j.leukres.2021.106747.Epub 2021 Nov 9. PMID: 34781054
43. Riva G, Nasillo V, Luppi M, Tagliafico E, Trenti T. Linking COVID-19, monocyte activation and sepsis: MDW, a novel biomarker from cytometry.EBioMedicine. 2021 Dec 15;75:103754. doi: 10.1016/j.ebiom.2021.103754. Epubahead of print. PMID: 34922322
44. Paolini A, Nasillo V, Lusenti B, Roncati L, Tagliafico E, Luppi M. Chromosome 16 changes do not always come for good. Int J Lab Hematol. 2021 Aug 1. doi: 10.1111/ijlh.13676. Epub ahead of print. PMID: 34337870.
45. Guglielmi C, Scarpitta R, Gambino G, Conti E, Bellè F, Tancredi M, Cervelli T, Falaschi E, Cosini C, Aretini P, Congregati C, Marino M, Patruno M, Pilato B, Spina F, Balestrino L, Tenedini E, Carnevali I, Cortesi L, Tagliafico E, Tibiletti MG, Tommasi S, Ghilli M, Vivanet C, Galli A, Caligo MA. Detection of Germline Variants in 450 Breast/Ovarian Cancer Families with a Multi-Gene Panel Including Coding and Regulatory Regions. Int J Mol Sci. 2021 Jul 19;22(14):7693. doi: 10.3390/ijms22147693. PMID: 34299313; PMCID: PMC8305371.
46. Tenedini E, Celestini F, Iapicca P, Marino M, Castellano S, Artuso L, Biagiarelli F, Cortesi L, Toss A, Barbieri E, Roncucci L, Pedroni M, Manfredini R, Luppi M, Trenti T, Tagliafico E. Automated capture-based NGS workflow: one thousand patients experience in a clinical routine framework. Diagnosis (Berl). 2021 Jun 16. doi: 10.1515/dx-2021-0051. Epub ahead of print. PMID: 34142509.
47. Riva G, Castellano S, Nasillo V, Ottomano AM, Bergonzini G, Paolini A, Lusenti B, Milić J, De Biasi S, Gibellini L, Cossarizza A, Busani S, Girardis M, Guaraldi G, Mussini C, Manfredini R, Luppi M, Tagliafico E, Trenti T. Monocyte Distribution Width (MDW) as novel inflammatory marker with prognostic significance in COVID-19 patients. Sci Rep. 2021 Jun 16;11(1):12716. doi: 10.1038/s41598-021-92236-6. PMID: 34135448; PMCID: PMC8209163.
48. Enzo E, Secone Seconetti A, Forcato M, Tenedini E, Polito MP, Sala I, Carulli S, Contin R, Peano C, Tagliafico E, Bicciato S, Bondanza S, De Luca M. Single-keratinocyte transcriptomic analyses identify different clonal types and proliferative potential mediated by FOXM1 in human epidermal stem cells. Nat Commun. 2021 May 4;12(1):2505. doi: 10.1038/s41467-021-22779-9. PMID: 33947848; PMCID: PMC8097075.
49. Toss A, Tenedini E, Piombino C, Venturelli M, Marchi I, Gasparini E, Barbieri E, Razzaboni E, Domati F, Caggia F, Grandi G, Combi F, Tazzioli G, Dominici M, Tagliafico E, Cortesi L. Clinicopathologic Profile of Breast Cancer in Germline ATM and CHEK2 Mutation Carriers. Genes (Basel). 2021 Apr 21;12(5):616. doi: 10.3390/genes12050616. PMID: 33919281; PMCID: PMC8143279.
50. Toss A, Piombino C, Tenedini E, Bologna A, Gasparini E, Tarantino V, Filieri ME, Cottafavi L, Giovanardi F, Madrigali S, Civallero M, Marcheselli L, Marchi I, Domati F, Venturelli M, Barbieri E, Grandi G, Tagliafico E, Cortesi L. The Prognostic and Predictive Role of Somatic BRCA Mutations in Ovarian Cancer: Results from a Multicenter Cohort Study. Diagnostics (Basel). 2021 Mar 21;11(3):565. doi: 10.3390/diagnostics11030565. PMID: 33801055; PMCID: PMC8003908.
51. Castellano S, Cestari F, Faglioni G, Tenedini E, Marino M, Artuso L, Manfredini R, Luppi M, Trenti T, Tagliafico E. iVar, an Interpretation-Oriented Tool to Manage the Update and Revision of Variant Annotation and Classification. Genes (Basel). 2021 Mar 8;12(3):384. doi: 10.3390/genes12030384. PMID: 33800487; PMCID: PMC8001268.
52. Corradini E, Buzzetti E, Dongiovanni P, Scarlini S, Caleffi A, Pelusi S, Bernardis I, Ventura P, Rametta R, Tenedini E, Tagliafico E, Fracanzani AL, Fargion S, Pietrangelo A, Valenti LV. Ceruloplasmin gene variants are associated with hyperferritinemia and increased liver iron in patients with NAFLD. J Hepatol. 2021 Mar 24:S0168-8278(21)00186-0. doi: 10.1016/j.jhep.2021.03.014. Epub ahead of print. PMID: 33774058.
53. Rontauroli S, Castellano S, Guglielmelli P, Zini R, Bianchi E, Genovese E, Carretta C, Parenti S, Fantini S, Mallia S, Tavernari L, Sartini S, Mirabile M, Mannarelli C, Gesullo F, Pacilli A, Pietra D, Rumi E, Salmoiraghi S, Mora B, Villani L, Grilli A, Rosti V, Barosi G, Passamonti F, Rambaldi A, Malcovati L, Cazzola M, Bicciato S, Tagliafico E, Vannucchi AM, Manfredini R. Gene expression profile correlates with molecular and clinical features in patients with myelofibrosis. Blood Adv. 2021 Mar 9;5(5):1452-1462. doi: 10.1182/bloodadvances.2020003614. PMID: 33666652; PMCID: PMC7948267.
54. Maffei R, Fiorcari S, Atene CG, Martinelli S, Scarfò L, Bonfiglio S, Maccaferri M, Ljungström V, Zucchini P, Forghieri F, Potenza L, Ghia P, Marasca R, Trenti T, Tagliafico E, Luppi M. A single-tube multiplex method for monitoring mutations in cysteine 481 of Bruton Tyrosine Kinase (BTK) gene in chronic lymphocytic leukemia patients treated with ibrutinib. Leuk Lymphoma. 2021 Mar 4:1-6. doi: 10.1080/10428194.2021.1894643. Epub ahead of print. PMID: 33663302.
55. Griguolo G, Dieci MV, Paré L, Miglietta F, Generali DG, Frassoldati A, Cavanna L, Bisagni G, Piacentini F, Tagliafico E, Cagossi K, Ficarra G, Prat A, Conte P, Guarneri V. Immune microenvironment and intrinsic subtyping in hormone receptor-positive/HER2-negative breast cancer. NPJ Breast Cancer. 2021 Feb 12;7(1):12. doi: 10.1038/s41523-021-00223-x. PMID: 33579951.
56. Parenti S, Rontauroli S, Carretta C, Mallia S, Genovese E, Chiereghin C, Peano C, Tavernari L, Bianchi E, Fantini S, Sartini S, Romano O, Bicciato S, Tagliafico E, Della Porta M, Manfredini R. Mutated clones driving leukemic transformation are already detectable at the single-cell level in CD34-positive cells in the chronic phase of primary myelofibrosis. NPJ Precis Oncol. 2021 Feb 4;5(1):4. doi: 10.1038/s41698-021-00144-9. PMID: 33542466; PMCID: PMC7862275.
57. Parenti S, Rabacchi C, Marino M, Tenedini E, Artuso L, Castellano S, Carretta C, Mallia S, Cortesi L, Toss A, Barbieri E, Manfredini R, Luppi M, Trenti T, Tagliafico E. Characterization of New ATM Deletion Associated with Hereditary Breast Cancer. Genes (Basel). 2021 Jan 21;12(2):136. doi: 10.3390/genes12020136. PMID: 33494414.
58. Forghieri F, Nasillo V, Paolini A, Bettelli F, Pioli V, Giusti D, Gilioli A, Colasante C, Acquaviva G, Riva G, Barozzi P, Maffei R, Potenza L, Marasca R, Fozza C, Tagliafico E, Trenti T, Comoli P, Longo G, Luppi M. NPM1-Mutated Myeloid Neoplasms with <20% Blasts: A Really Distinct Clinico-Pathologic Entity? Int J Mol Sci. 2020 Nov 26;21(23):8975. doi: 10.3390/ijms21238975. PMID: 33255988; PMCID: PMC7730332.
59. Carretta C, Mallia S, Genovese E, Parenti S, Rontauroli S, Bianchi E, Fantini S, Sartini S, Tavernari L, Tagliafico E et al: Genomic Analysis of Hematopoietic Stem Cell at the Single-Cell Level: Optimization of Cell Fixation and Whole Genome Amplification (WGA) Protocol. Int J Mol Sci 2020, 21(19).
60. Bettelli F, Giusti D, Morselli M, Colaci E, Nasillo V, Pioli V, Gilioli A, Iotti S, Galassi L, Giubbolini R, Colasante C, Catellani H, Barozzi P, Lagreca I, Vallerini D, Maffei R, Franceschini E, Mussini C, Banchelli F, D’Amico R, Marasca R, Narni F, Potenza L, Comoli P, Luppi M, Forghieri F. Epidemiology and clinical outcomes of latent tuberculosis infection in adults affected with acute leukemia or aplastic anemia: a retrospective single-center study. Ann Hematol. 2020 Sep;99(9):2201-2203. doi: 10.1007/s00277-020-04191-3. Epub 2020 Jul 23. PMID: 32699943.
61. Maffei R, Benatti S, Atene CG, Debbia G, Zucchini P, Potenza L, Luppi M, Fiorcari S, Marasca R. Selective inhibition of PI3Kγ affects survival and proliferation of chronic lymphocytic leukemia B cells. Leuk Lymphoma. 2020 Feb;61(2):455-459. doi: 10.1080/10428194.2019.1666376. Epub 2019 Nov 14. PMID: 31724453.
62. Maffei R, Maccaferri M, Arletti L, Fiorcari S, Benatti S, Potenza L, Luppi M, Marasca R. Immunomodulatory effect of ibrutinib: Reducing the barrier against fungal infections. Blood Rev. 2020 Mar;40:100635. doi: 10.1016/j.blre.2019.100635. Epub 2019 Oct 31. PMID: 31699465.
63. Riva G, Nasillo V, Tagliafico E, Trenti T, Comoli P, Luppi M: COVID-19: more than a cytokine storm. Crit Care 2020, 24(1):549.
64. Romagnani A, Rottoli E, Mazza EMC, Rezzonico-Jost T, De Ponte Conti B, Proietti M, Perotti M, Civanelli E, Perruzza L, Catapano AL et al: P2X7 Receptor Activity Limits Accumulation of T Cells within Tumors. Cancer Res 2020, 80(18):3906-3919.
65. Toss A, Molinaro E, Venturelli M, Domati F, Marcheselli L, Piana S, Barbieri E, Grandi G, Piombino C, Marchi I et al: BRCA Detection Rate in an Italian Cohort of Luminal Early-Onset and Triple-Negative Breast Cancer Patients without Family History: When Biology Overcomes Genealogy. Cancers (Basel) 2020, 12(5).
66. Riva G, Nasillo V, Tagliafico E, Trenti T, Luppi M: COVID-19: room for treating T cell exhaustion? Crit Care 2020, 24(1):229.
67. Forghieri F, Nasillo V, Bettelli F, Pioli V, Giusti D, Gilioli A, Mussini C, Tagliafico E, Trenti T, Cossarizza A et al: Acute Myeloid Leukemia in Patients Living with HIV Infection: Several Questions, Fewer Answers. Int J Mol Sci 2020, 21(3).
68. Raimondo D, Remoli C, Astrologo L, Burla R, La Torre M, Verni F, Tagliafico E, Corsi A, Del Giudice S, Persichetti A et al: Changes in gene expression in human skeletal stem cells transduced with constitutively active Gsalpha correlates with hallmark histopathological changes seen in fibrous dysplastic bone. PloS one 2020, 15(1):e0227279.
69. Prat A, Guarneri V, Pare L, Griguolo G, Pascual T, Dieci MV, Chic N, Gonzalez-Farre B, Frassoldati A, Sanfeliu E et al: A multivariable prognostic score to guide systemic therapy in early-stage HER2-positive breast cancer: a retrospective study with an external evaluation. Lancet Oncol 2020, 21(11):1455-1464.
70. Smargiassi A, Bertacchini J, Checchi M, Potì F, Tenedini E, Montosi G, Magarò MS, Amore E, Cavani F, Ferretti M, Grisendi G, Maurel DB, Palumbo C. WISP-2 expression induced by Teriparatide treatment affects in vitro osteoblast differentiation and improves in vivo osteogenesis. Mol Cell Endocrinol. 2020 Aug 1;513:110817. doi: 10.1016/j.mce.2020.110817. Epub 2020 May 18. PMID: 32439416.